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### Prof Linus Pauling Therapy for cancer: from http://www.vitamincfoundation.org/unified.htm
Dr Linus Pauling's Unified Theory of Cardiovascular Disease
… . In the sixties, Pauling waged almost single handedly a successful crusade against atmospheric testing of nuclear weapons; warning of the future fallout in the form of genetic diseases, cancers and numerous other serious health problems. His relentless work in this area yielded nuclear test banning treaties among the Soviets, US and other major powers, resulting in a cleaner, safer environment for us all.
… , in fact we have direct experimental evidence for it, is that vitamin C is rapidly converted into other substances, oxidation products and these other substances, these oxidation products have been shown to have greater value against cancer than vitamin C itself. So if you take large doses of vitamin C you produce large amounts of these other substances,…
… I'm not against drugs when they are properly used and have said so over and over again. We advocate for every patient with cancer taking high doses of vitamin C as an adjunct to appropriate conventional therapy and I agree with Dr Cameron that surgery - he was a surgeon - surgery is often the best treatment for a malignant condition if the malignant tumor can be removed and sometimes, for a few kinds of cancer, chemotherapy is known to have much value and, for some kinds, high energy radiation has value even though chemotherapy and high energy radiation have pretty serious side effects, are damaging to the body as a whole, nevertheless, the benefit may outweigh the disadvantages.
- one book : Cancer: Nutrition and Survival by Steve Hickey and Hilary Roberts , Print: $29.21
http://www.lulu.com/content/193438 , 296 pages, 6.00" x 9.00", ISBN: 1-4116-6339-X, © 2005 ,
Description: Microevolution explains what cancer is, how it develops and how to eradicate it. Cancer occurs in multi-celled organisms when cells escape the body's controls and behave like their single-celled ancestors. Such changes, triggered by oxidative damage, result in faulty cell division.
Animals and plants have developed ways to stop their cells reverting to primitive forms. Hence, anticancer substances are common throughout nature. Therapies based on these take advantage of metabolic differences between cancer cells and healthy cells, to destroy cancer while helping healthy cells. Clinical trials are needed to test such non-toxic therapies.
Biological research suggests that cancer is a treatable condition. Although current data is not sufficient to indicate the degree of life extension achievable, many terminal patients might die of other causes, before the cancer kills them. Cancer patients deserve to be offered this opportunity.
2005 Contribution of the Year - Steve Hickey PhD and Hilary Roberts PhD
At the top of the list, two warriors, Steve Hickey PhD and Hilary Roberts PhD, pharmacology graduates from Manchester, England, whose landmark books have disclosed the falsehoods disseminated by skeptics of vitamin C therapy.
The latest of these, CANCER, NUTRITION AND SURVIVAL will open the door for many cancer patients to opt for "ascorbate" therapy rather than the harsh ineffective treatments now being offered by conventional medicine. Cancer patients who seek out intravenous vitamin C treatment are likely to survive longer (by years in some instances) than with chemo or radiation treatment. Their earlier book, THE RIDICULOUS DAILY ALLOWANCE reveals the flawed science behind the establishment of the RDA for vitamin C which has led to the mistaken public impression that most adults consume sufficient amounts of vitamin C.
In fact, 100% of the human species is deficient.
Customers who bought Cancer: Nutrition and Survival also bought:
· Ascorbate (Hilary Roberts, Steve Hickey)
· Ridiculous Dietary Allowance (Steve Hickey, Hilary Roberts)
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### Dr. RATH's cure for Cancer: (Go and see also the full page about Dr. RATH in Nutritherapies)
http://www.dr-rath-foundation.org/ or http://www.drrath.com/
Natural Eradication of Cancer. Matthias RATH claims CANCER HALTED with VITAMIN C /LYSINE/PROLINE and GREEN TEA EXTRACT.
Dr. Rath's revolutionary discoveries in the natural control of cancer metastasis, heart disease, high blood pressure, high cholesterol, diabetes and other chronic health conditions challenge conventional medicine. They are reshaping current beliefs about health and disease while changing millions of lives around the globe.
What you learn by enrolling in Dr. Rath's Seminar on Cellular Health will empower you with the knowledge you need to take control of your health and life.
# DETAILS:
All human cells are surrounded by collagen fibres and connective tissue. In order to grow and expand, healthy cells need to break down this extra-cellular barrier that confines them. This process is essential for life and for this reason, cells produce and secrete various enzymes that digest connective tissue components, including collagen and elastin.
It is important that these enzymes, called matrix metalloproteinases or MMPs, be regulated by sets of activators and inhibitors so that the integrity of the connective tissue is never compromised.
Excessive disintegration of connective tissue accompanies pathology and once this disintegration occurs, infectious cancer cell microbes (including viruses) can invade tissues. In extreme cases, such as in cancer, the excessive production of digestive enzymes and the disintegration of collagen and connective tissue by cancer cells are the dangerous mechanisms by which these cells invade and spread to other organs.
In his Cellular Health Series book "Cancer", Dr. Rath documents his scientific discovery that certain nutrients, including L-lysine, are powerful natural inhibitors of collagen-digesting enzymes. It is this discovery that has put Matthias Rath, Inc. on the path to defeating this devastating disease.
# The Spread of Cancer Can Be Controlled
In the laboratory at Matthias Rath, Inc. scientists have conducted research with live cells to provide answers to various scientific questions. Once they understood the mechanism by which cancer cells metastasized, there was one critical question that the Matthias Rath Inc. researchers sought to answer: How could they naturally inhibit the invasion of cancer cells through collagen and connective tissue in a way that would enhance the body's own capacity for managing disease?
In seeking this answer, the researchers designed an experiment so that they could first investigate the ability of cancer cells to digest through a collagenous matrix and then develop a method to control it. For this purpose, the researchers used specific vials that included partitions made of collagenous material similar to that which surrounds cells in the body. In the upper chamber of some vials, they incubated cancer cells with nutritive agents. In the upper chamber of other vials, they incubated cancer cells without nutritive agents.
Afterwards, the researchers were able to determine which group of cancer cells was able to digest the collagen membrane and migrate to the lower chamber.
The results of the experiment were remarkable. A simple combination of nutrients was able to stop cancer cells from invading the collagen matrix!
The most powerful nutrient combination contained vitamin C, the amino acids L-lysine and L-proline, and a polyphenol fraction of green tea known as Epigallocatechin Gallate (EGCG).
# Scientific Publications on Nutrients and Cancer: http://www4.dr-rath-foundation.org/NHC/researcharchive.html#cance
# Physicians Speak
Since May of 2003, I have used Dr. Rath's nutrient synergy recommendations as both adjunct and main modality in cancer patients and those who suffered from cardiovascular diseases.
The progress that my patients made has been the best of my 15 years of medical practice.
Among 200 cancer cases that I had, I lost 24 patients who came to me with stage IV of cancer, with more than one secondary and metastasis. The remaining cancer patients are doing very well. Their tumors went into full remission or became fibroid tumors.
In cardiovascular cases, the results are spectacular. In almost every case, I have seen improvements of varying degrees. In hypertension, osteo-arthritis, tinnitus, hyper-cholesterolemia, myocardial-infarction, and stroke cases, I observed the improvements within weeks or even days.
For my patients with diabetes, especially non-insulin dependent patients, I have seen very rapid response rates, usually within the first few weeks of treatment. In those patients, I have been able to gradually reduce their medications as well. In at least ten cases, patients that would have otherwise required amputation have been able to avoid that procedure by implementing Dr. Rath's nutrient synergy recommendations.
Wong Ang Peng, M.D. Wong's Nature Cure Center Singapore
# Examples of Cancer Cases: Natural Eradication of Cancer:
1. Patient : Wong Kon Fung (Malaysia) ... Age: 32 years Diagnosis: Left Breast Cancer (Infiltrating Carcinoma Grade III) ... Conventional Treatment: Lumpectomy Dr. Rath's Cellular Health™ Program: Started in March 10, 2005
- BEFORE Dr.Rath's Cellular Healt Program : March, 2005, Cyst in the right breast 3 mm
- AFTER Dr. Rath's Program : July, 2005 Ultrasound, No cysts or masses in the right or left breast
2. Patient : Rocy Chong (Malaysia)... Age: 46 years ... Dr. Rath's Cellular Health™ Program: Started in November, 2004
- BEFORE Dr.Rath's Cellular Health™ Program : November, 2004, Fibroadenoma lump in the left breast (10x5x5mm)
- AFTER Dr. Rath's Program : December, 2004, Medical exam stated that lump in the breast has been cleared
3. Patient's Name: Soam Meng Chuu (Malaysia) ... Age: 50 years ... Conventional Treatment: Chemotherapy five cycles, Dr. Rath's Cellular Health™ Program: Started in March 11, 2004
- BEFORE Dr.Rath's Cellular Health Program : March 2004, Stage 2B Cervical Cancer
- AFTER Dr. Rath's Program : December 2005, No dysplastic or malignant cells seen on the Pap Smear
Cellular Health™ Series - Cancer, by Matthias Rath, M.D.Cancer provides a summary of the progress of Cellular Health in the battle against several forms of cancer, infectious diseases, and other serious conditions. It substantiates the fact that cancer - the second most common disease after heart disease - can be beaten naturally. This book discloses key mechanisms, which describe how cancer cells spread in the body and how this process can be blocked in a natural way. Dr. Rath provides scientific evidence that cancer can be successfully controlled without chemotherapy, radiation, or other dangerous and ineffective approaches used today by conventional medicine.
#Testimonials Cancer ;
Thousands of people worldwide have benefited their health as a result of taking advantage of Dr. Rath's scientific discoveries. The following experiences represent just a few examples of the many testimonials we have received regarding the effectiveness of Dr. Rath's natural Cellular Medicine approach.
- … A few years ago my wife was diagnosed with breast cancer and, needless to say, I was motivated to do extensive research on the underlying cause and treatment.
My wife was advised to have surgery, and I knew that chemotherapy such as Tamoxifen would be recommended even though a number of surveys show that chemotherapists have said they would not take chemotherapy themselves or recommend it for their families.
Chemotherapy drugs are toxic substances and known poisons and usually don't cure cancer or extend life. They really do not improve the quality of life either.
Yet the use of chemotherapy or radiation for cancer can significantly impact the immune system and over a period of time have serious consequences.
During my research I had previously reviewed some of Dr. Matthias Rath's scientific findings and found that the spread of cancer cells could be inhibited by using specific natural nutrients. This was very important since most of the cancer fatalities result from invasion of cancer cells into other organs and tissues.
My wife and I had visited Dr. Rath's research facility in Fremont, California where we were able to meet with the research scientists and see for ourselves that a combination of L-lysine, Vitamin C, L-proline and EGCG which stops the spread of breast cancer cells 100%.
So in addition to focusing on making important dietary changes we started taking these natural cellular nutrients. By doing this we have minimized cancer recurrence but most important avoided harmful side effects that often accompanies conventional cancer therapy.
The synergistic combination of Vitamin C, Proline, Lysine and EGCG should be considered for anyone with the diagnosis of cancer.
When we realize that nearly 1.5 million Americans are diagnosed with cancer every year and since it is the number two cause of death, it is prudent for most of us to take proactive steps to prevent this disease through diet and by following Dr. Rath's Cellular Health recommendations.
Vic Herlacher, M.D. www.vherlacher.com San Juan Capistranio, CA.
- Evelyn Olguin Age: 58 -- Diagnosis: Multiple Myeloma -- Date of Diagnosis: February 2003
I was diagnosed with multiple myeloma (leukemia) in February 2003. I was told that I needed a bone marrow transplant. I was tired, weak, and forgetful. My vision was blurred, and I cried a lot. I couldn't be out of the house for more than an hour without being exhausted for three days. I couldn't walk. My left leg would drag, and I would become easily tired. My memory was poor. I had to make sure that I ate consistently throughout the day. The skin literally hung from my body, and I didn't have any muscle tone.
In July 2003, my sister introduced me to Dr. Rath's discoveries. In August 2003, I called the nutritionist and described my health problems. I was placed on a protocol, which consisted of cellular nutrients.
My vision and gallbladder improved. I would get severe discomfort in my abdomen in the afternoon and that improved. My breathing also improved. I gained weight and began sleeping well. The color of my skin also improved.
Now, I am driving again. I am gaining my independence and starting my life over. Cellular nutrients helped me tolerate my cancer medication.
As of December 2003, I now have the strength to go back to work. I am energetic. My personality has returned. I am grateful for the support I have received from Dr. Rath's staff. They have always been very supportive and loving. They listened to my needs and carried me through difficult times. Now, I can share my positive experience with a smile and give thanks for their support.
CONCLUSION: After using cellular nutrients for only three months, Evelyn Olguin's IgG level decreased by 337 mg/dl and is in normal range, Evelyn is still healthy as of January 2005.
- Sheela Pandharipande Age: 69 Diagnosis: Colon Cancer Date of Diagnosis: November 2002
I began experiencing health problems in July 2002. I felt exhausted all the time, and I was too weak to even walk up a few steps. A blood test revealed that my hemoglobin level was 8.9 g/dL. (Normal hemoglobin levels for women are 12-16 g/dL.) I was given a blood transfusion and also treated with iron therapy. However, I continued to feel exhausted, and I lost my appetite. In November 2002, I was diagnosed with colon cancer.
I underwent surgery, but I continued to suffer from a poor appetite and weakness. Three weeks after the operation, I remained bedridden. In December 2002, I volunteered to participate in a pilot study in India for cancer that was being sponsored by Dr. Rath Research Institute. Within just one week, I experienced a dramatic improvement in my condition.
Three months after starting cellular nutrients, my hemoglobin levels increased from 8.9 g/dL to 10.2 g/dL. My doctor told me that the tumor marker level (CA-125) in my blood had decreased from 8.6 to 3.5. I feel energetic, and I am taking a short walk every day. My appetite has returned, and my weight has increased from 105 pounds to 122 pounds. My quality of life has tremendously improved. I am very grateful to Dr. Rath for helping give me a better life.
CONCLUSION: After only three months of using cellular nutrients, Sheela Pandharipande's tumor marker for colon cancer decreased significantly by 5.06, from 8.6 to 3.54. Sheela's hemoglobin levels increased by 1.3 g/dl, from 8.9 g/dL to 10.2 g/dL and her red blood count increased by 1.32 million/cmm. She also gained 17 pounds.
- Sally Holt Age: 65 Diagnosed: March 2002 Diagnosed Condition: Ovarian Adenocarcinoma, Grade 2 with the mixed endometroid and papillary serous pattern
I was diagnosed with ovarian cancer, which was surgically removed in March 2002. After surgery, a CT scan was done and another tumor was found. My tumor marker CA-125 level was 25. Doctors wanted to remove the tumor with surgery and do chemotherapy. I refused both and searched for alternative treatments. One of my friends introduced me to cellular nutrients, and we attended Dr. Rath's lecture in May 2002 at the Palace of Fine Arts in San Francisco. I was almost in tears listening to Dr. Rath.
After attending the lecture, I started taking cellular nutrients and informed my physician. My doctor told me that I was playing with my life. A few months later, I went to my physician and the CT scan showed no signs of the tumor. My CA-125 level had gone down to four. As of December 2003, my CA-125 level was three. I am very excited about the results. I feel energetic. I have no complaints, no GI symptoms, and no pelvic masses.
CONCLUSION: After four months of using cellular nutrients, Sally Holt's tumor marker CA-125 level decreased significantly from 25 to four, and the tumor shrank from 22mm to 12mm. A continuing decrease of Sally's tumor marker level is still being observed. The unique synergistic action of cellular nutrients was able to achieve what pharmaceutical drugs could not. Sally is still cancer free as of January 2005.
- John Asel Age: 64 Diagnosis: Renal Cell Carcinoma: Maximum classified as Stage 1+ or 2 only because of the tumor size - 10 lbs. (tumor diameter on left kidney 8 cm) Date of Diagnosis: November 2000
My name is John Asel. I was diagnosed with renal cell carcinoma in November of 2000. I lost my left kidney to renal cell carcinoma. I was diagnosed with having a tumor on my kidney and, at that time, a registered nurse who is a good friend of ours told us about Dr. Rath. I've been using cellular nutrients since last August. I haven't taken any other medications, just cellular nutrients. I haven't had many physical symptoms of the renal cell carcinoma, such as weight loss or gain, and I feel much better. I walk two miles a day, plus I do Fit-Links at the [gym]. On December 30th, I had a CT scan and the tumor showed signs of necrosis, which meant it was actually dying from within. My appetite and color are good. I am back working in the office. The moons on my fingers are much better. It's just been wonderful. This is now the third month after my previous scan, and the tumor just looks like a shadow on my liver.
There were two spots on my lung that have disappeared. There is no new evidence of any cancer in my system anywhere. I feel that without cellular nutrients, I would not be here.
CONCLUSION:: As of January 2005, John Asel feels great and is energetic. John's liver and lungs are clear.
UPDATE: As of February 2006, John Asel still feels great and has no symptoms of a disease. He sent us his recent medical report and told us that his doctor at Duke Medical Center with whom he met in February, 2006, was very pleased because the tumors on the liver and the adrenal gland are necrotic. His doctor told him that the blood supply has been cut off to the tumors and they are dying from within. The pancreas is normal and there is no change in the lungs. Since John feels great and has no symptoms of cancer, his doctor did not force him to have any preventive conventional treatment and said "lets leave it alone".
Here is what John wrote us: "Again thank you for your help. I will keep on the accelerated vitamin program till the next scan. If there is anything I can do to assist the Rath organization please let me know. It works."
- Sylvia Fregoso Age:44 Diagnosis: Breast Cancer (left breast) Date of Diagnosis: January 2000
At present, her doctors say Sylvia only has scar tissue in the lymph nodes of her neck.
Sylvia was offered chemo in December 2003 and February 2004. She declined the treatments both times. Sylvia is still cancer free as of January 2005.
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## Dr Robert F. Cathcart: Vitamin C, Titrating to Tolerance http://www.orthomed.com/titrate.htm
Allergy, Environmental, and Orthomolecular Medicine, Orthopedic Medicine
127 Second Street, Suite 4, Los Altos, California, USA, Fax:650-949-5083 -
TITRATING TO BOWEL TOLERANCE
The maximum relief of symptoms which can be expected with oral doses of ascorbic acid is obtained at a point just short of the amount which produces diarrhea. The amount and the timing of the doses are usually sensed by the patient.
The physician should not try to regulate exactly the amount and timing of these doses because the optimally effective dose will often change from dose to dose. Patients are instructed on the general principles of determining doses and given estimates of the reasonable starting amounts and timing of these doses. I have named this process of the patient determining the optimum dose, TITRATING TO BOWEL TOLERANCE.
The patient tries to TITRATE between that amount which begins to make him feel better and that amount which almost but not quite causes diarrhea.
I think it is only that excess amount of ascorbate not absorbed into the body which causes diarrhea; what does not reach the rectum, does not cause diarrhea.
It is interesting to know, when one speculates on the exact cause of this diarrhea, that while a hypertonic solution of sodium ascorbate is being administered intravenously, the amount of ascorbic acid tolerated orally actually increases.
THE 100 GRAM COLD
When a person is ill the amount of ascorbic acid he can ingest without diarrhea being produced increases somewhat proportionally to the severity or the toxicity of the disease. A cold severe enough to permit a person to take 100 grams of ascorbic acid per 24 hours during the peak of the disease, I call a 100 GRAM COLD.
INDIVIDUAL RESPONSES
Perhaps one of the most important principles in ORTHOMOLECULAR MEDICINE is BIOCHEMICAL INDIVIDUALITY (18). Every individual responds to substances differently. Vitamin C is no exception. However, at least 80% of my patients tolerated ascorbic acid well. Admittedly, there were relatively few older patients in my practice. Infants, small children, and teenagers tolerate ascorbic acid well and can take, proportionate to their body weight, larger amounts than adults.
Older adults tolerate lesser amounts and have a higher percentage of nuisance difficulties. Patients with multiple food intolerances may have more difficulties but should attempt taking ascorbate because of benefits often obtained.
For several years while I was treating only sick people with ascorbic acid, I was unaware of the number of people who had nuisance problems with maintenance doses. The tolerance of the sick person to ascorbate is so high as to prevent many of the complaints one would have if he were well. When ascorbic acid is prescribed to a sick person, the beneficial effect is obvious enough so that few complain of the gas and diarrhea.
With illness the effects of an overdose do not last long because of the rapid rate of utilization.
It is important for the physician to understand the principles of treating this vast majority of tolerant persons. Patients frequently underdose themselves and need professional guidance to push the doses to effective levels. The small number of persons, especially elderly persons, intolerant to oral doses are in my experience able to take intravenous ascorbate without difficulties. Additionally, patients with severe problems may need to be treated intravenously if very high doses will have to be maintained for some time for adequate suppression of symptoms.
… The following problems should be expected with increased incidence with severe depletion of ascorbate: disorders of the immune system such as secondary infections, rheumatoid arthritis and other collagen diseases, allergic reactions to drugs, foods and other substances, chronic infections such as herpes, or sequelae of acute infections such as Guillain-Barre' and Reye's syndromes, rheumatic fever, or scarlet fever; disorders of the blood coagulation mechanisms such as hemorrhage, heart attacks, strokes, hemorrhoids, and other vascular thrombosis; failure to cope properly with stresses due to suppression of the adrenal functions such as phlebitis, other inflammatory disorders, asthma and other allergies;
problems of disordered collagen formation such as impaired ability to heal, excessive scarring, bed sores, varicose veins, hernias, stretch marks, wrinkles, perhaps even wear of cartilage or degeneration of spinal discs; impaired function of the nervous system such as malaise, decreased pain tolerance, tendency to muscle spasms, even psychiatric disorders and senility; and cancer from the suppressed immune system and carcinogens not detoxified; etc. Note that I am not saying that ascorbate depletion is the only cause of these disorders, but I am pointing out that disorders of these systems would certainly predispose to these diseases and that these systems are known to be dependent upon ascorbate for their proper function.
CANCER
I have avoided the treatment of cancer patients for legal reasons; however, I have given nutritional consults to a number of cancer patients and have observed an increased bowel tolerance to ascorbic acid.
Were I treating cancer patients, I would not limit their ascorbic acid ingestion to a set amount but would titrate them to bowel tolerance. Ewan Cameron's advice against giving cancer patients with widespread metastasis large amounts of ascorbate too rapidly at first should be heeded.
He found that sometimes extensive necrosis or hemorrhage in the cancer could kill a patient with widespread metastasis if the vitamin was started too rapidly (16). Hopefully, in the future ascorbic acid will be among the initial treatments given cancer patients. The additional nutritional needs of cancer patients are not limited to ascorbic acid, but certainly the stress involved with having the disease depletes ascorbate levels in the body.
Ascorbate should be used in cancer patients to avert disorders of ascorbate deficiency in various systems of the body including the immune system.
References:
- Cameron, E. and Pauling, L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci. USA, 73:3685-3689, 1976.
- Cameron, E. and Pauling, L. The orthomolecular treatment of cancer: Reevaluation of prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci. USA, 75:4538-4542, 1978.
- Cameron, E. and Pauling, L. Cancer and Vitamin C. The Linus Pauling Institute for Science and Medicine, Menlo Park, 1979.
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### Dr Fonorow's cure for cancer: http://www.thecureforheartdisease.com/owen/CancerCure.htm
The lack of vitamin C in humans has probably caused more suffering than all other genetic defects combined. Scientists who have studied these matters have blamed heart disease, cancer and many other chronic diseases on this single genetic defect that caused our ancestors to loose their ability to make vitamin C.
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## Vitamin C Intravenous to CURE Cancer: (Go and see also the full page about Vitamin C Intravenous of Dr. KLENNER)
# VITAMIN C injections to cure cancers:
From : http://www.seanet.com/~alexs/ascorbate/198x/smith-lh-clinical_guide_1988.htm
Clinical Guide to the Use of Vitamin C
The Clinical Experiences of Frederick R. Klenner, M.D., abbreviated, sumarized and annotated by Lendon H. Smith, M.D.
… Briefly, Vitamin C does attenuate most virus infections by aiding the production of interferon, controls many cancers, relieves some depression, modifies much pain and changes the course of many diseases, like multiple sclerosis, amyotrophic lateral sclerosis, spider bites, the bites of poisonous insects and reptiles. The watchword is, "If in doubt, give Vitamin C."
Dr. Klenner points out that the cancer seems to hit those with a hereditary tendency; a virus grows more eagerly in the susceptible. If there is a family tendency, oral C in large doses as a preventative makes sense.
Cancer: He cites Schlegel's (Tulane University) use of ascorbic acid (1.5 grams a day only) in preventing bladder cancer recurrence. "This is the so called wasted Vitamin C."
He "demonstrated that in the presence of ascorbic acid, carcinogenic metabolites will not develop in the urine. They suggested that spontaneous tumor formation is the result of faulty tryptophan metabolism while urine is retained in the bladder." Other researchers report that the depletion of mast cells from guinea pig skin was due to ascorbic acid deficiency. It suggests Vitamin C is necessary for the formation and maintenance of mast cells.
Vitamin C will control myelocytic leukemia with 25-30 grams orally daily. "How long must we wait for someone to start continuous ascorbic acid drip for two to three months, giving 100 to 300 grams each day, for various malignant conditions?
Small basal cell epithelioma: 30% Vitamin C ointment.
He cites a disturbing study: particles resembling viruses were found in some breast milk samples of women with breast cancer. Could this help to explain why some cancers seem to be "inherited?" It makes sense that all members of cancer prone families should be taking at least ten grams of C daily.
His protocol for treating cancer is printed here in total, although I do not understand the rationale for some of the ingredients. All of this is designed to kill the cancer cells by shoring up the immune system. He even recognized the therapeutic value for a positive attitude.
1. Use radioactive cobalt when and where indicated.
2. Give 45 grams of sodium ascorbate intravenously every twelve hours for one month. Then use 60 to 65 grams in 500 cc of normal saline or 5% dextrose in water for five days a week until a cure is obtained. It usually takes five months.
3. Each bottle is to contain one gram of calcium gluconate, a cc of some B complex, plus 1,200 mg of thiamin, 300 mg of pyridoxine, and 600 mg of niacinamide.
4. Oral sodium ascorbate, 5, 10, 20, grams daily. The dose depends upon the bowel tolerance.
5. Vitamin A palmitate, 50,000 units, daily, orally.
6. Pantothenic acid, (B5) one gram orally four times a day.
7. Amino acid protein powder with all the eighteen amino acids. 60 tablets each day or, if a powder, several tablespoons daily. This supports the immune system and the enzymes. Tyrosine should be taken separately, if possible, as this one makes the others work better; 500 mg tablets-six daily.
8. In addition, a high protein diet using white chicken meat, fresh fish, chicken livers, and brown-shelled eggs. Beef (but once a week) should be as lean as possible: lean stew beef or sirloin tip are the best but have the butcher grind it three times. Hamburgers? Only once a week. No sugar and no starches. Fruit and fruit juices are permitted. Almonds are excellent.
9. 30 to 40 apricot almonds should be chewed every day in divided doses until a continuous bitter almond taste develops. At this point the patient cuts the dose in half. "This will form cyanide by way of the stomach acid. Cyanide will kill cancer cells. Vitamin C will protect one against the lethal effects of cyanide. It is the antidote. 500 mg tablets of vitamin B17 are available. One after each meal and at bed time." (Not everyone would agree with this part of the therapy. Cancer victims are still getting amygdalin B17, as injections from Mexico, but there is some doubt as to its efficacy. LHS)
10. Vitamin E, d-alpha tocopheryl acetate, 400 International unit size, 3,200 units daily. Don't take iron with it.
11. One pint of grape juice daily.
12. B complex tablets with 100 mg of each of the B's and 100 mcg of B12. Six to eight tablets daily. Theragran-M or a similar capsule with all the minerals to replace what is being pulled out by the C.
13. Maintain the hemoglobin at 13 grams.
14. Keep a good attitude.
He reported a case of a man with lymph glands all over his body. He got the above treatment and although the glands increased in size for a while, his liver and spleen were back to normal size in four months. Dr. Klenner noticed a 'parachute-like' substance in the urine. Microscopic examination revealed they were clumps of cancer cells.
Another case was that of a woman who had an adenocarcinoma of two years duration. She had had chemotherapy, two surgeries and extensive radiation over her chest, especially the neck area where the cancerous glands were. The cancer had spread to her lungs, her abdomen and six glands in her neck. Dr. Klenner gave her the above protocol. In three months the lesion in her lung had cleared and gone were the glands in her neck. After six months of intravenous Vitamin C and the B complex, the abdominal masses had disappeared, but she could not swallow food. The radiation had scarred her esophagus beyond dilatation and she refused more surgery. The cancer was gone; she died from starvation due to the radiation.
Dr Klenner summarized this paper with this: "The results suggest that larger daily amounts could be given in a hospital with faster results. I would suggest at least 100 grams in 1000 cc of fluid and given every twelve to 24 hours. The vitamins and the calcium gluconate also must be given." He thought interferon could be assayed while the patient is in the hospital. "How long will it take for the general population to challenge the drug cartel?"
… Vitamin C will control the side effects of radiation including radiation burns. "Who can say what 100 to 300 grams given intravenously daily for several months might accomplish in cancer? The potential is so great and the employment so elementary that only the illiterate will continue to deny its use."
Vitamin C inhibits the deaminizing enzymes from the damaged cells (due to burns, injury, infections). Histamine is produced by these enzymes. The shock is controlled. [Chambers & Pollock; Clark & Rossiter]
# Could ascorbic acid have anti-cancer features?
Schlegel[50] from Tulane University has been using 1.5 grams ascorbic acid daily to prevent recurrences of cancer of the bladder. He and biochemist Pipkin have been able to demonstrate that in the presence of ascorbic acid, carcinogenic metabolites will not develop in the urine. They suggest that spontaneous tumor formation is the result of faulty tryptophan metabolism while urine is retained in the bladder. Schlegel termed ascorbic acid "An Anticancer Vitamin". Along this line Glick and Hosoda[51] reported on work by Von Numers and Pettersson that the depletion of mast cells from guinea pigs skin was due to ascorbic acid deficiency. The possibilities indicated are that vitamin C is necessary either directly or indirectly for formation of mast cells, or for their maintenance once formed or both. Ascorbic acid will control myelocytic leukemia provided 25 to 30 grams are taken orally each day.
One can only speculate on what massive therapy would do in all forms of cancer. Many pathologic conditions are cured by giving 5 million to 100,000 million units of penicillin as an intravenous drip over a period of 4 to 6 weeks. How long must we wait for someone to start continuous ascorbic acid drip for 2 to 3 months, giving 100 to 300 grams each day, for various malignant conditions?
# In Malignancy.
The part very large doses of ascorbic acid given intravenously over a prolonged period offers a medical challenge. From cabbage and tomatoes grown in the carbon-14 chambers radioactive ascorbic acid can be extracted, which can be used in tracer studies. At least one research team has demonstrated that in cancer all available "C" is mobilized at the site of the malignancy. Lauber and Rosenfeld reported that "C" is mobilized from the tissues of the body and selectively concentrated in traumatized areas.
In one hopeless case we administered 17 grams daily for 92 consecutive days without changing the blood or urine levels from that associated with scurvy. This is the reason we believe a dose range of 100 grams to 300 grams daily by continuous intravenous drip for a period of several months might prove surprisingly profitable. Blood chemistry should be followed daily with such an investigation. Schlegel found that even a dose of 1.5 grams a day, by mouth, would prevent bladder cancer.
# Mononucleosis
Dr. Klenner felt mono is related to cancer because the same virus (Epstein-Barr) is found in Burkett's lymphoma. The disease, mono, can be eliminated with an I.V. of C in just a few days, "The actual time being directly proportional to the amount of the vitamin employed in relation to the severity of the infection."
(Most of us use Dr. Cathcart's formula for the amount of C to be given: "I think this is a 50 gram disease: some fever, generalized aches, but ambulatory.") In one patient who was given the last rites by her church, the girl's mother took things into her own hands when the attending physician refused to give ascorbic acid. In each bottle of I.V. fluid she would secretly and quickly "tap in" 20 -30 grams of Vitamin C. The patient made an uneventful recovery. Her mother has her BS in nursing and has been a long time advocate of massive "C" therapy. (100 gram disease: 102-103 degree temperature, holding down fluids but needs to stay in bed, miserable. 20 gram disease: 104 degree temperature, semi-comatose, somewhat dehydrated; hospitalization a good idea.)
# Pulsed Intravenous Vitamin C (PIVC) Therapy http://tomlevymd.com/archiveissue6.htm
Vitamin C has already been extensively and unequivocally documented to readily cure a wide range of infectious diseases, including many viral syndromes considered incurable even today (Stone, 1972; Smith, 1988, Levy, 2002). In reviewing a great amount of this information, it becomes apparent that for most infectious diseases, especially viral ones, the only clinical failures of vitamin C appear to occur when a large enough amount of vitamin C cannot be effectively delivered to the invading microorganisms.
With this in mind, then, a more effective dosing and/or delivery system of vitamin C to the various tissues of the body should further improve the clinical efficacy of this agent. In cancer, Riordan et al. (1995) demonstrated the likelihood that vitamin C was an effective anti-tumor therapy as long as high enough concentrations of it could be achieved inside the tumor(s).
These researchers also concluded that oral vitamin C supplementation was unlikely to produce blood levels of vitamin C high enough to have a direct killing effect on a given tumor. Later, in studying a certain line of cancer cells and the ability of vitamin C to kill those cancer cells, Casciari et al. (2001) elegantly demonstrated this point. They showed that the rapid intravenous infusion of vitamin C as sodium ascorbate in combination with alpha lipoic acid was effective in reaching vitamin C levels that were toxic to the cancer cells.
They also showed that a fat soluble analogue of vitamin C, phenyl-ascorbate, was able to kill cancer cells effectively at a dose roughly three times lower than seen with unaltered vitamin C.
All of the conclusions reached by Casciari et al. noted above support the proposed concept that most clinical failures of vitamin C for infections or other medical conditions relate to inadequate delivery. They administered as much as 60,000 mg of vitamin C over an 80-minute period, a very sizable dose and a fairly rapid administration by most standards of current usage. Yet such a large and rapidly administered infusion of vitamin C will not always be clinically effective. This still does not mean that the vitamin C might not be the optimal treatment for a given condition.
… This vitamin C-induced hypoglycemia should prove to be a very desirable effect clinically, however. Severe hypoglycemia has already been safely and deliberately induced in a protocol that has been in existence for over 70 years now. Known as insulin potentiation therapy ( www.iptq.org ), intravenous insulin (roughly 20 to 40 units) is given rapidly to induce hypoglycemia. As hypoglycemia becomes manifest, minidoses of cancer chemotherapeutic agents are administered. Such small doses, in the presence of insulin-induced hypoglycemia, appear to be facilitated in their transport across the cell membrane pathways such that the drugs reach killing concentrations inside cancer cells at much lower dosage levels. Traditional chemotherapy can often be given without causing the otherwise inevitable loss of hair seen with the much larger doses.
Casciari, J., N. Riordan, T. Schmidt, X. Meng, J. Jackson, and H. Riordan. (2001) Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours. British Journal of Cancer 84(11):1544-1550.
# Cancer: Intravenous Vitamin C Effective Treatment
Studies during the 1970s first suggested administration of high doses of ascorbate might provide a clinical benefit for treating cancer, but later studies using the same high doses found no benefit. However, researchers now say the original studies used intravenous and oral ascorbate, while subsequent studies used only oral administration. Recognizing those differences might account for the disparate clinical outcomes, Mark Levine and colleagues at the National Institutes of Health...
read more: http://www.newmediaexplorer.org/sepp/2005/09/13/cancer_intravenous_vitamin_c_effective_treatment.htm
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### Dr Irwin STONE http://vitamincfoundation.org/stone/chap1-11.htm
"THIS MAY BE THE MOST IMPORTANT BOOK ON HEALTH EVER WRITTEN" - National Health Federation Bulletin -
THE HEALING FACTOR / VITAMIN C Against Disease, By Irwin Stone
With forewords by Nobel Prizewinners Dr. Linus Pauling and Dr. Albert Szent-Gyorgyi.
Vitamin C may save your life! A noted biochemist reveals for laymen the exciting research into ascorbic acid's powers against such deadly enemies as cancer, heart disease, strokes, mental illness, old age, diabetes, arthritis, kidney disease, hepatitis -- even cigarette smoking!
… In 1969 it was reported that laboratory tests conducted at the National Cancer Institute showed that ascorbic acid was lethal to certain cancer cells and harmless to normal tissue. This might be the long awaited breakthrough in cancer therapy. Intensive study and research should immediately be concentrated to investigate these possibilities.
… ## CANCER
Over half a million people in the United States develop cancer each year and over 280,000 will die in the year ahead. More than 700,000 people are under treatment at all times. It is the number two scourge and one of every five of us is likely to be afflicted; under present conditions it will send one of every eight of us to the grave.
Cancer is not a single disease entity but a large group of closely related, yet different, diseases. Essentially, cancerous growth is uncontrolled tissue development and expansion and is due to the tissue losing the normal restraints on cell divisions and growth. The cancer grows in a wild manner at the expense of the surrounding normal tissues. Cancer can arise in any organ or tissue of the body and, like the infectious diseases, the causes are varied and different. In severity it can range from a relatively innocuous minor illness to a life-threatening disease. The pattern of cancer incidence has been changing over the years, with fewer stomach and uterine cancers and more lung cancer and leukemia.
Present-Day Cancer Therapy
In the therapy of cancer, the first important step is a diagnosis. After diagnosis, the physician has three different paths or a combination of them from which to choose: irradiation, chemotherapy, or surgery. Irradiation is localized exposure to X rays or to the radiant energy of radioactive sources, such a s radium or cobalt 60, to try to kill the fast-growing cancerous tissue without doing too much damage to the rest of the body. Chemotherapy involves the use of chemical substances that tend to damage the cancer tissue more than the normal cells and thus retard the cancer development. Surgery, of course, is the direct approach of going in and physically removing the cancerous tissue, when possible.
Ever since the discovery of ascorbic acid in the early 1930s, there has been a vast amount of animal experimentation and clinical research conducted on the relationship of ascorbic acid to cancer.
This has resulted in a mass of conflicting and confusing reports as to the value of ascorbic acid in cancer treatments. Some investigators reported good results in their tests, others reported no effects on the growth of cancer tissue, while still others took the stand that tit stimulated tumor growth. Detailed discussion of the possible reasons for the conflicts of opinion in this work is beyond the scope of this chapter, except to speculate that it may be due to the wide variety of experimental animals, cancer types, and experimental conditions employed by the numerous investigators.
As a first step in future cancer research h on ascorbic acid, a responsible, unbiased research agency should review this large volume of early work and assess its value in the light of the more recent research and newer concepts. Any research work which may be required to resolve these unanswered questions and conflicting opinions should be conducted. Because of the long-standing disagreement nd the resulting confusion, there has reportedly been a tendency for research workers to shy away from this area.
One thing, however, is certain. Cancer and its present-day therapy are intense biochemical stresses which deplete the bodies of cancer victims of their ascorbic acid. The irradiation, the surgery, or the chemotherapy with highly toxic materials, are all severe biochemical stresses. Biochemical stresses, in the majority of the mammals which are able to produce their own ascorbic acid, cause them to produce more ascorbic acid to combat the stresses. Because of their defective genetic inheritance, mammals such as guinea pigs, monkeys, and man are dependent on their food intake for ascorbic acid and their response to stress is ascorbic acid depletion.
Experiments on rats, mice, and guinea pigs are enlightening on this point. When rats and mice (animals that can make their own ascorbic acid) are exposed to cancer-producing agents (carcinogens), they start producing much more ascorbic acid in their livers (1). However, when guinea pigs (animals which, like man, cannot produce their own ascorbic acid) are exposed to the same carcinogens, their ascorbic acid is used up and not replaced (2); to quote the authors of this 1955 paper, when mammals are exposed to carcinogens this will "excite an increased demand for this compound (ascorbic acid) to which the animals capable of synthesizing it respond by over protection, whereas in those lacking this power the store is depleted."
In another experiment on guinea pigs, Russell (3), in 1952, showed that cancers developed sooner in guinea pigs exposed to carcinogens and fed a diet deficient in ascorbic acid as compared to guinea pigs exposed to the same carcinogens but on an adequate ascorbic acid diet. Can we extrapolate this observation to humans and say that people who do not fully "correct" their genetic disease, hypoascorbemia, by continuously taking high levels of ascorbic acid are more susceptible to cancer than fully "corrected" individuals?
An opposite view is taken in the 1955 paper by Miller and Sokologg (3), who proposed that a prescorbutic state in the cancer victim may have beneficial effects on cancer patients during radiation therapy. To settle this question once and for all should not entail much additional research.
A person afflicted with cancer will almost always be nearly depleted of ascorbic acid before the usual course of therapy is begun. Radiation therapy using radiant energy in the form of X rays or gamma rays is a potent form of biochemical stress for the body. Exposing a cancer victim to radiant energy only further aggravates a serious shortage of this metabolite and prevents the body from maintaining biochemical homeostasis under the onslaughts of the additional radiation stresses. There have been other papers published which suggested giving ascorbic acid to cancer patients before exposure to radiation and noting its benefits (4).
In spite of these many suggestions, further large-scale conclusive research has not been conducted and the practice is little used. These scientists, in their clinical work used, at most, a few grams of ascorbic acid a day. This is another virgin area of megascorbic therapy, just awaiting someone to go in and try it.
Cancer chemotherapy is the use of certain chemicals to selectively poison the cancer cells without killing the patient. We will not go into the chemistry of the different materials used other than to say that they are all very poisonous and dangerous (host toxic). This, of course, limits the amounts which can be given the patient at any one time.
One group of materials used in cancer chemotherapy is the so-called nitrogen mustards, which are derivatives of the mustard gases of World War I ; you can conceive the type of material used in this therapy. While the chemotherapeutic agent will attack the cancer cells, the patient is left without means to overcome the toxic manifestations of the medicament. In spite of the fact that ascorbic acid has been known to be an efficient detoxicating agent for poisonous substances (see Chapter 24) no reports have been found in the medical literature for the combined administration of these toxic medicaments along with large doses of ascorbic acid as a supportive measure. The presence of high optimal levels of ascorbic acid might also improve the toxic action on the cancer cells(5), but we will never know unless it is thoroughly investigated. The potential benefits, if successful, would seem to make these clinical trials an urgent necessity.
The data contained in the 1969 paper from dean Burk and his group (5) at the National Cancer Institute are very pertinent at this point. They showed that ascorbate is highly toxic to the cancer cells they used (Ehrlich ascites carcinoma cells) and caused profound structural changes in the cancer in their laboratory cultures.
They mention that:
The great advantage that ascorbates ... possess as potential anticancer agents is that they are, like penicillin, remarkably nontoxic to normal body tissues, and they may be administered to animals in extremely large doses (up to 5 or more grams per kilogram) without notable harmful pharmacological effects.
5 grams per kilogram on a 70-kilogram adult would amount to 350 grams of ascorbic acid per day.
They further state:
In our view, the future of effective cancer chemotherapy will not rest on the use of host-toxic compounds now so widely employed, but upon virtually host-nontoxic compounds that are lethal to cancer cells, of which ascorbate ... represents an excellent prototype example.
They also bring out the amazing fact that in the screening program that has been going on for years to find new cancer-killing materials at the Cancer Chemotherapy National Service Center, ascorbic acid has been bypassed, excluded from consideration, and never tested for its cancer-killing properties. The reason given for not screening ascorbic acid is even more fantastic -- ascorbic acid was too nontoxic to fit into their program!
An almost immediate confirmation of Dean Burk's proposals was contained in the research conducted at Tulane University School of Medicine by Schlegel and coworkers and published in 1969 (5). It was shown that bladder cancer due to smoking and other causes could be prevented by ascorbic acid. They recommended the intake of 1.5 grams of ascorbic acid a day to avoid the recurrence of bladder tumors.
The remaining are of cancer therapy, surgery, is one where ascorbic acid may now be used to some extent. It may be used, not so much for its direct effect on the cancer, but for its beneficial effects in wound healing. For this purpose it is generally used at a gram or so a day, which may be quite inadequate to handle the biochemical stresses of anesthesia, surgical shock, and hemorrhagic shock on an already depleted cancer victim. Full "correction" of the victim's hypoascorbemia may require instituting a preoperative. operative, and postoperative regime at much higher levels. Additional research on a regime of this sort may uncover possibilities for survival and cure far beyond today's hopes.
Use of Ascorbic Acid in Cancer Therapy
Present-day cancer therapy thus virtually ignores the potential of ascorbic acid as a biochemical stress combatant, a detoxicant, an anticarcinogenic agent, a means for maintaining homeostasis, and a mechanism for improving the well-being and survival of the patient.
During the past forty years there have been many papers published in the medical literature in which ascorbic acid has been used for cancer therapy. But no one in all this time has consistently used ascorbic acid in the large doses which may be required to demonstrate a therapeutic effect. There has never been a well-planned program to test ascorbic acid in cancer therapy and no one has used more than a gram or, at most, several grams a day (except in one case, discussed later).
Deucher (4), in 1940, used up to 4 grams of ascorbic acid a day for several days in treating his cancer patients and found it had a remarkably favorable effect on their general condition and increased their tolerance to X rays. On the other hand, Szenes (4), in 1942, stated that the administration of ascorbic acid is contraindicated in tumor patients because it intensifies tumor growth.
It was also use in combination with vitamin A, which only further complicated the picture, in a series of tests. Von Wendt, in 1949, 1950, and 1951, and Huber, in 1953, used 2 grams of ascorbic acid a day combined with large doses of vitamin A and reported favorable effects. Schneider, in 1954, 1955, and 1956, also used ascorbic acid, 1 gram daily in combination with vitamin A and found it "arrested" cancers and that it was more useful against epitheliomas than against sarcomas (6).
Of interest also are three papers by McCormick (7), in 1954, 1959,and 1963, in which he postulates the theory that the factor which preconditions the body to the development of cancer is the degenerative changes caused by continued low levels of ascorbic acid in the body. He gives evidence to support his hypothesis and states, "We maintain that the degree of malignancy is determined inversely by the degree of connective tissue resistance, which in turn is dependent upon the adequacy of vitamin C status." McCormick's ideas have never been adequately tested.
Some additional evidence for the support of this hypothesis comes from the work of Goth and Littmann (8), in 1948, who found that cancers most frequently originate in organs whose ascorbic acid levels are below 4.5 mg % and rarely grow in organs containing ascorbic acid above this concentration. Fully corrected individuals should have tissue levels of ascorbic acid in excess of this seemingly critical 4.5 mg %.
Detoxication of Carcinogens
Another piece of research which has not been properly followed through was reported by Warren (9), in 1943, who showed that certain carcinogens, anthracene, and 3:4-benzpyrene (the type of carcinogen in tobacco smoke), are susceptible to oxidation in the presence of ascorbic acid. In the oxidized form they are no longer carcinogenic.
Here is a possible means for preventing the induction of cancer after exposure to carcinogens merely by maintaining the necessary levels of ascorbic acid in the exposed tissues. This is an area of research that has been stagnant for two decades, which would have the most important consequences for smokers or city dwellers forced to breathe polluted air, or for others exposed to carcinogens.
Leukemia
Leukemia is a cancerous disease of the blood-forming tissues in which there is an over production of the white blood cells (leukocytes). Different types of leukemia are named after the different varieties of leukocytes involved in the disease process. The over-production of the leukocytes causes, i most cases,a marked rise in the number of white blood cells in the circulating blood.
Research work connecting ascorbic acid, the blood elements, and leukemia was started not long after the discovery of ascorbic acid. Stephen and Hawley (10), in 1936, showed that when the blood was separated into plasma, red blood cells, and white blood cells, there was a 20- to 30-fold concentration of ascorbic acid in the white blood cells.
Hemorrhage, being a symptom of both leukemia and scurvy, caused clinicians to early investigate the use of ascorbic acid in leukemia because of its dramatic effects on hemorrhage in scurvy. Eufinger and Gaehtgens (11), in 1936, reported giving 200 milligrams of ascorbic acid a day and came to the conclusion that it had a normalizing influence on the blood picture. Schnetz (11), in 1940, came to the same conclusion: when the leukocytes are high ascorbic acid tends to reduce them, and when they are low it tends to increase them. He used 200 to 900 milligrams a day by injection.
Here is a marked example of the ancient mammalian mechanism of ascorbic acid homeostasis.
In 1936, Plum and Thomsen (12), injecting 200 milligrams of ascorbic acid a day, obtained remissions in two cases of myeloid leukemia, and Heinild and Schiedt (12), using two 100-milligram injections daily, obtained uncertain, variable results. Thiele (12), in 1938, using 500 milligrams of ascorbic acid a day by injections, found no effect in chronic myeloid leukemia, while both Palenque (4) and van Nieuwenhuizen (12), in 1943, observed slight decreases in the white blood counts. Such variable and confusing results are typical when submarginal an inadequate dosages are employed.
Vogt, in 1940, in a review of the work conducted on ascorbic acid in leukemia up to that time, cited twenty-one references. About the only conclusion he reached was that there were high deficits of ascorbic acid in leukemics. These deficits and the very low blood plasma levels of ascorbic acid in leukemics were confirmed in later papers by Kyhos et al., in 1945, and Waldo and Zipf, in 1955, and yet, in all these years, no one was inspired to get away from these pitifully small doses of ascorbic acid and make some clinical tests with heroic doses (13).
In a leukemic, the biochemical stresses of the disease process has reduced the body stores of ascorbic acid to very low levels. Any ascorbic acid circulating in the blood has been scavenged and locked in the excessive numbers of white blood cells contained in the blood. The plasmas level of ascorbic acid is usually zero or close thereto. A zero level in the blood plasma means that he tissues of the body are not being supplied with this most important metabolite. The ascorbic acid contained in the leukocytes are unavailable for the tissues. The tissues are in a condition of biochemical scurvy and this explains why these depleted tissues are so susceptible to the characteristic hemorrhaging of leukemia and the infections that kill so many of the leukemics.
A leukemic is not only suffering from leukemia but also from a bad case of biochemical scurvy. To correct this condition, ascorbic acid has to be administered in sufficiently large doses not only to saturate the excess of white blood cells but to provide adequate spillover into the blood plasma and tissues so that the seriously ill leukemic will be given a fighting chance to combat the disease. This may require the administration of ascorbic acid at the rate of 25 or more grams per day, as noted in the following case of leukemia treated with megascorbic levels of ascorbic acid.
This case history, reported by Greer (14), in 1954, was of a seventy-one-year-old executive of an oil company, who was first seen for alcoholic cirrhosis of the liver and polycythemia (excess of red blood cells); some months earlier, symptoms of chronic myocarditis had appeared. Shortly thereafter, he was hospitalized and passed a large uric acid bladder stone, and a diagnosis of chronic myelogenous leukemia was established. He also had intractable pyorrhea and his remaining 17 teeth were removed at one operation. At this time he started taking ascorbic acid at the rate of 24.5 grams to 42 grams per day, "because he reported he felt much better when he took these large doses." Since the diagnosis of leukemia and the removal of the teeth, "the patient has repeatedly remarked about his feeling of well-being and has continued his vocation as executive of an oil company."
On two occasions, at the insistence of his attending physician, he stopped taking the ascorbic acid and both times his spleen and liver enlarged and became tender, his temperature rose to 101o, and he complained of general malaise and fatigue (typical leukemia symptoms). When he started the ascorbic acid again, the symptoms cleared and his temperature became normal within 6 hours. Over a year and a half later the patient had a severe attack of epidemic diarrhea and died of acute cardiac decompensation. At the time of death, the spleen was firm, not tender, and had not enlarged since taking the ascorbic acid. The doctor also reported that "the polycythemia, leukemia, cirrhosis, and the myocarditis had shown no progression: in the year and a half while taking the ascorbic acid.
The case history concludes with the statement, "The intake of the huge doses of ascorbic acid appeared essential for the welfare of the patient."
One would believe that the exciting results in this 1954 case would be immediately picked up and explored further by the leukemia groups in the national government or the foundations that are continually asking the public for more research money, but no follow-up work has been found in the medical literature of the past sixteen years.
If megascorbic therapy could do so much for an aged leukemic with so many other complications, what could it do for the young, uncomplicated leukemic? The answer to this question could be obtained easily and each day lost may mean more lives wasted. At the present time, millions of dollars are spent in screening all sorts of poisonous chemicals for use in leukemia, while a harmless substance like ascorbic acid, with so much potential, lies around neglected and ignored.
Recent work has brought forward evidence that human leukemia may be caused by a virus. While viruses are known to product cancer like diseases in animals, none have been proved in man. If the cause of human leukemia is eventually shown to be due to a virus, the rationale for the use of megascorbic therapy in leukemia will be further strengthened because it has been shown that ascorbic acid is a potent, wide-spectrum, nontoxic virucide when used at megascorbic dosage levels (see Chapter 13).
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